Trusted by Top Companies
Clinical Trial Finance Is Still Where Operations Loses Money, Time, and Control
What Cloudbyz CTFM Delivers
70–80% faster budget creation with reusable templates and activity-based costing
60–70% reduction in payment cycle time through EDC-triggered automation
Zero manual reconciliation, every payment traces back to its clinical source
Real-time accruals and forecasting that eliminate month-end scrambles
50–60% fewer “where’s my payment?” inquiries through self-service site portals
Audit-ready financial records with complete trails from budget to payment
More Than Tracking: Clinical Trial Finance as an Execution System
Most tools track budgets and payments. Cloudbyz executes them.
- Connects protocol-driven budgets directly to site negotiations
- Automates site payments using EDC data
- Generates audit-ready invoices with full compliance
- Provides real-time accrual visibility for finance teams and CFOs
- Fully integrated with Cloudbyz CTMS and the broader eClinical platform
- Creates a closed-loop financial system from budget to payment
- Ensures complete traceability of every dollar spent
Core Capabilities
Study Budget Planning
Build Accurate Budgets 70–80% Faster From Protocol to Cost in Days, Not Weeks
Cloudbyz replaces spreadsheet-based budgeting with a structured, protocol-driven approach. Map clinical activities directly to costs, reuse templates across therapeutic areas, and manage multi-version budgets with full audit trails, so your finance and operations teams start every study with a defensible, accurate financial plan.
Includes:
- Protocol-to-cost mapping with activity-based costing methodology
- Reusable budget templates by therapeutic area, region, and protocol type
- Site grant roll-up from individual site budgets to study-level totals
- Multi-version management with full audit trails tracking every change
- Budget Wizard for rapid ROM estimates during planning and bid defense
- Excel import and rate card libraries for historical cost benchmarking
Site Budgeting & Negotiation Tracking
Accelerate Site Activation With Collaborative, Auditable Negotiation That Replaces Email Chaos
Site budget negotiation is one of the biggest sources of activation delays. Cloudbyz brings every negotiation into a structured workflow with FMV-guided rates, subject cost linkage to the visit plan, and real-time approval routing, so you can negotiate faster, maintain compliance, and keep a complete audit trail of every rate decision.
Includes:
- Site-level budgets with procedure-by-procedure cost breakdown
- FMV-guided rate recommendations with historical benchmarking
- Subject costs linked directly to visit plan / schedule of events
- Real-time negotiation workflows with redline tracking and version history
- Multi-tier approval routing with configurable escalation rules
- Amendment management with retroactive rate application and true-up logic
Site Payment Automation
Pay Sites Accurately and On-Time With Zero Manual Reconciliation
Slow site payments damage relationships, slow enrollment, and force sites to subsidize trial costs out of pocket. Cloudbyz automates the entire payment lifecycle from EDC visit completion to payment generation eliminating the weeks-long lag between clinical activity and financial settlement. Every payment traces directly to its clinical source with full referential integrity.
Includes:
- EDC-data triggered payments, visit completion automatically generates payables
- Milestone and task-based payment triggers (IRB approval, site startup, etc.)
- Advance payments, holdbacks, split payments, and override capabilities
- Multi-currency support with FX tracking and gain/loss reporting
- SMO hierarchy support with pass-through payments and configurable mark-ups
Invoicing & Reconciliation
Eliminate Financial Leakage With Audit-Ready Invoicing and Automated Reconciliation
Manual invoicing and reconciliation are where clinical finance teams lose the most time and money. Cloudbyz generates proforma invoices directly from approved payables, validates every line item against the source budget, prevents duplicates system-wide, and syncs bi-directionally with your ERP, transforming reconciliation from a complex Excel exercise into a system-driven process.
Includes:
- Automated proforma invoice generation from approved payables
- System-wide duplicate prevention for visits, invoices, and expense claims
- Multi-level validation engine with configurable business rules
- Bi-directional ERP/AP integration (Workday, SAP, Oracle, NetSuite, Dynamics 365)
- Automated payment reconciliation with referential integrity back to clinical source
Forecasting & Accruals Reporting
Give CFOs and Finance Teams the Real-Time Visibility They Need
For the CFO, the accuracy of clinical trial accruals determines audit outcomes and investor confidence. Cloudbyz calculates accrued liabilities in real time work completed but not yet paid and generates journal-entry-ready files for your ERP. No more month-end scrambles. No more stale data. Finance teams get the visibility they need for accurate ASC 730 compliance and proactive spend management.
Includes:
- Real-time accruals reporting: (Completed Visits × Price) + Approved Expenses – Paid Invoices
- Cash flow forecasting based on enrollment trends, contract values, and historical performance
- Budget variance tracking with milestone-based projections
- Journal entry file generation (CSV/API) for ERP sub-ledger integration
- Burn rate analysis and scenario-based spend projections across the trial portfolio
Global Compliance & Tax
Run Global Trials With Confidence — Every Payment Compliant and Audit-Ready
Running trials across 80+ countries introduces VAT, withholding tax, reverse charge mechanisms, and region-specific regulatory requirements. Cloudbyz handles global tax complexity natively applying the right rules based on sponsor and site location, flagging recoverable VAT, calculating withholding deductions, and maintaining complete audit trails for every transaction.
Includes:
- VAT / GST / WHT capture with country-specific rule engine
- 21 CFR Part 11 compliance with electronic signatures and system controls
- GDPR-compliant data handling and privacy controls
- Complete audit trails logging every financial action, approval, and modification
- Sunshine Act / transparency reporting for investigator payments
Portals & Collaboration
Eliminate “Where’s My Payment?” With Self-Service Transparency
Sites spend countless hours chasing payment status. Sponsors spend equally long answering those inquiries. Cloudbyz portals give every stakeholder the visibility they need, sites can track their payment pipeline, submit invoices and expenses, and download remittance advice in real time. Sponsors get a single command center for financial oversight across all studies and sites.
Includes:
- Sponsor portal with cross-study financial dashboards and oversight controls
- Site portal for self-service invoice submission, expense claims, and payment tracking
- Real-time payment pipeline visibility: Visit Completed → Pending Approval → Invoiced → Paid
- Document exchange with configurable distribution lists and attachment handling
- Dispute resolution workflow with reason codes and resolution tracking
Reports & Dashboards
Make Data-Driven Financial Decisions With Real-Time Analytics
Cloudbyz turns trial financial execution data into actionable intelligence. Role-based dashboards surface the right information for the right stakeholder from study managers tracking budget versus actuals to CFOs monitoring portfolio-wide spend trajectories. Every report is drill-able, exportable, and always current.
Includes:
- Role-based dashboards tailored to finance, operations, and executive stakeholders
- Budget vs. actuals tracking with variance analysis and trend reporting
- Payment status dashboards: pending, approved, invoiced, paid across all sites
- Forecasting reports with enrollment-driven spend projections
- BI integration and self-service report builder for custom analytics
AI Agents for Clinical Trial Finance
AI Agents That Remove the Manual Work Without Losing Control
Clinical trial finance is high-volume, rule-heavy, and full of repetitive tasks that consume skilled personnel. Cloudbyz AI Agents automate the work that slows teams down, from budget anomaly detection to payment reconciliation, while maintaining audit trails and human oversight at every step.
AI Budget Intelligence Agent
AI Payment Reconciliation Agent
AI Accruals & Forecasting Agent
AI Finance Chatbot
Built for Trust and Compliance
Human-in-the-loop approvals for all AI-generated recommendations
Full audit trail of every AI action, recommendation, and override
Configurable rules aligned to your SOPs and financial governance
Secure governance aligned to GxP and regulatory expectations
Why Cloudbyz CTFM Is Different
Closed-Loop Financial Execution
Every payment traces from clinical event (EDC visit completion) through budget validation, invoice generation, and ERP settlement with full referential integrity. No manual reconciliation required.
Unified With CTMS and the eClinical Platform
Cloudbyz connects financial workflows directly to CTMS execution, study start-up, and downstream operational processes, eliminating the data silos that plague every other financial tool.
Built on Salesforce
Enterprise-grade scalability, security, and global performance, with configuration flexibility for complex organizations. HIPAA, GDPR, and GxP compliant out of the box.
Designed for Global Complexity
Multi-currency, multi-country tax engines, SMO hierarchies, split payments, and FX tracking — built for organizations running trials across 80+ countries, not retrofitted onto a domestic-only system.
Built for the Teams Who Own Trial Finance
Sponsors
Gain real-time financial control across your trial portfolio. Build defensible budgets, automate site payments, close accruals faster, and give your CFO the visibility they demand.
CROs
Manage financial operations for multiple sponsors in parallel. Standardize budgeting, streamline site payments, and eliminate the reconciliation burden that consumes your finance team.
Site Networks & SMOs
Get paid faster with transparent payment pipelines. Submit invoices and expenses through self-service portals. Track payment status in real time without chasing sponsors or CROs.
Enterprise-Grade Security and Auditability
